Generic: Recombinant follicle stimulating hormone rfsh All side effects
Generic name
Recombinant Follicle Stimulating Hormone (rFSH)
Common side effects
- Injection site reactions such as pain, redness, or swelling
- Mild stomach discomfort or bloating
- Headache
- Nausea or vomiting
- Mood swings
Serious side effects
- Effect: Ovarian hyperstimulation syndrome (OHSS)
- Description: A potentially serious condition characterized by swollen and painful ovaries, abdominal pain, rapid weight gain, trouble breathing, and nausea or vomiting
- Warning: Seek immediate medical attention if you experience severe abdominal pain, persistent nausea or vomiting, decreased urination, or difficulty breathing
- Effect: Ectopic pregnancy
- Description: When a fertilized egg implants outside the uterus, usually in a fallopian tube, causing severe abdominal pain and vaginal bleeding
- Warning: Contact your healthcare provider immediately if you experience sharp pelvic pain or heavy vaginal bleeding
- Effect: Allergic reaction
- Description: Rare but possible allergic reactions such as rash, itching, swelling, severe dizziness, or trouble breathing
- Warning: Seek emergency medical help if you notice any signs of a serious allergic reaction
Rare side effects
- Effect: Ovarian torsion
- Description: A rare but serious condition where the ovary twists on its blood supply, causing sudden severe abdominal pain
- Frequency: Rare occurrence
- Effect: Thromboembolism
- Description: Formation of a blood clot that can block a blood vessel, potentially leading to serious complications
- Frequency: Rare occurrence
Mild side effects
- Effect: Injection site reactions
- Description: These symptoms usually subside within a few hours to a couple of days
- Effect: Mild stomach discomfort
- Description: Temporary and typically resolves on its own
Long term side effects
- Effect: Multiple pregnancies
- Description: Increased risk of multiple pregnancies such as twins or triplets due to stimulation of multiple egg production
- Prevention: Discuss with your healthcare provider the option of single embryo transfer to reduce the risk
Allergic reactions
- Reaction: Skin rash
- Symptoms: Itchy, red, or inflamed skin
- Advice: Stop using the medication and consult your doctor
- Reaction: Swelling
- Symptoms: Facial swelling, hives, or swelling of the tongue or throat
- Advice: Seek immediate medical help
Precautions
- Inform your doctor of any allergies to medications
- Discuss any history of ovarian cysts or hormone-related cancers
- Use caution if you have a history of blood clots or stroke
Interactions
- Avoid concurrent use of clomiphene citrate or gonadotropin-releasing hormone
Overdose effects
- Severe abdominal pain
- Rapid weight gain
- Shortness of breath
Management tips
- Ensure proper injection technique to minimize injection site reactions
- Stay well-hydrated to reduce the risk of OHSS
- Keep a journal of symptoms and report any changes to your healthcare provider
Frequency
- Common:
- Injection site reactions
- Mild stomach discomfort
- Headache
- Rare:
- Ovarian torsion
- Thromboembolism
Side effects by age group
- Adults:
- Injection site reactions
- Mild stomach discomfort
- Mood swings
- Elderly:
- Injection site reactions
Side effects by gender
- Female:
- Ovarian hyperstimulation syndrome
- Ectopic pregnancy
- Male:
- None
Patient experiences
- Positive:
- Increased chances of conception
- Improved fertility outcomes
- Negative:
- Severe abdominal pain due to OHSS
- Mood swings and temporary discomfort