Generic: Recombinant follicle stimulating hormone rfsh All side effects

Generic name

Recombinant Follicle Stimulating Hormone (rFSH)

Common side effects

  • Injection site reactions such as pain, redness, or swelling
  • Mild stomach discomfort or bloating
  • Headache
  • Nausea or vomiting
  • Mood swings

Serious side effects

    • Effect: Ovarian hyperstimulation syndrome (OHSS)
    • Description: A potentially serious condition characterized by swollen and painful ovaries, abdominal pain, rapid weight gain, trouble breathing, and nausea or vomiting
    • Warning: Seek immediate medical attention if you experience severe abdominal pain, persistent nausea or vomiting, decreased urination, or difficulty breathing
    • Effect: Ectopic pregnancy
    • Description: When a fertilized egg implants outside the uterus, usually in a fallopian tube, causing severe abdominal pain and vaginal bleeding
    • Warning: Contact your healthcare provider immediately if you experience sharp pelvic pain or heavy vaginal bleeding
    • Effect: Allergic reaction
    • Description: Rare but possible allergic reactions such as rash, itching, swelling, severe dizziness, or trouble breathing
    • Warning: Seek emergency medical help if you notice any signs of a serious allergic reaction

Rare side effects

    • Effect: Ovarian torsion
    • Description: A rare but serious condition where the ovary twists on its blood supply, causing sudden severe abdominal pain
    • Frequency: Rare occurrence
    • Effect: Thromboembolism
    • Description: Formation of a blood clot that can block a blood vessel, potentially leading to serious complications
    • Frequency: Rare occurrence

Mild side effects

    • Effect: Injection site reactions
    • Description: These symptoms usually subside within a few hours to a couple of days
    • Effect: Mild stomach discomfort
    • Description: Temporary and typically resolves on its own

Long term side effects

    • Effect: Multiple pregnancies
    • Description: Increased risk of multiple pregnancies such as twins or triplets due to stimulation of multiple egg production
    • Prevention: Discuss with your healthcare provider the option of single embryo transfer to reduce the risk

Allergic reactions

    • Reaction: Skin rash
    • Symptoms: Itchy, red, or inflamed skin
    • Advice: Stop using the medication and consult your doctor
    • Reaction: Swelling
    • Symptoms: Facial swelling, hives, or swelling of the tongue or throat
    • Advice: Seek immediate medical help

Precautions

  • Inform your doctor of any allergies to medications
  • Discuss any history of ovarian cysts or hormone-related cancers
  • Use caution if you have a history of blood clots or stroke

Interactions

  • Avoid concurrent use of clomiphene citrate or gonadotropin-releasing hormone

Overdose effects

  • Severe abdominal pain
  • Rapid weight gain
  • Shortness of breath

Management tips

  • Ensure proper injection technique to minimize injection site reactions
  • Stay well-hydrated to reduce the risk of OHSS
  • Keep a journal of symptoms and report any changes to your healthcare provider

Frequency

  • Common:
    • Injection site reactions
    • Mild stomach discomfort
    • Headache
  • Rare:
    • Ovarian torsion
    • Thromboembolism

Side effects by age group

  • Adults:
    • Injection site reactions
    • Mild stomach discomfort
    • Mood swings
  • Elderly:
    • Injection site reactions

Side effects by gender

  • Female:
    • Ovarian hyperstimulation syndrome
    • Ectopic pregnancy
  • Male:
    • None

Patient experiences

  • Positive:
    • Increased chances of conception
    • Improved fertility outcomes
  • Negative:
    • Severe abdominal pain due to OHSS
    • Mood swings and temporary discomfort